| Lec # | TOPICS | LECTURERS | KEY DATES | 
|---|---|---|---|
| Part I. Principles of Tissue Engineering: Scaffolds and Cells | |||
| 1 | Course Overview/Clinical Problems for Tissue Engineering Solution Introduction to Tissue Engineering in China Scaffolds: Introduction Scaffolds: Collagen-GAG Analogs of Extracellular Matrix  | Prof. Spector, MIT / Prof. Cui, Tsinghua University Prof. Cui, Tsinghua University Prof. Spector, MIT Prof. Yannas, MIT  | |
| 2 | Cells: Liver Cells Scaffolds: Recent Advances in Tissue Engineering  | Yingxin Xu, M. D., and Qingling Feng, Ph. D., Tsinghua University Prof. Langer, MIT  | |
| 3 | Scaffolds: Free-Form Manufacturing Scaffolds: Self-Assembled Proteins Review  | Prof. Yan, Tsinghua University Dr. S. Zhang, MIT Prof. Spector, MIT  | |
| 4 | Cells: Sources Cells: Differentiated versus Stem Cells  | Dr. C. Vacanti, MIT Prof. Spector, MIT  | |
| Part II. Principles of Tissue Engineering: Cells and Regulators | |||
| 5 | Scaffolds: Biomimetics Design Cells: Effects of Culture Conditions Review  | Prof. Cui, Tsinghua University Dr. L. Freed, MIT Prof. Spector, MIT  | Homework 1 due | 
| 6 | Quiz 1 | Homework 2 due | |
| 7 | Regulators: Response to Mechanical Loading Regulators: Roles of Environmental Factors  | Prof. Grodzinsky, MIT Dr. Vunjak-Novakovic, MIT  | |
| 8 | Cells: Embryonic and Other Stem Cell for Tissue Engineering Gene Therapy Regulators: Gene Transfer Wedded to Tissue Engineering  | Prof. Guo, Tsinghua University Dr. Zhijie Chang, Tsinghua University Prof. Evans, Harvard Medical School  | |
| Part III. Practice of Tissue Engineering: Clinical Applications | |||
| 9 | Applications: Skin and Peripheral Nerve Nerve Repair Discussion: Clinical Applications  | Prof. Yannas, MIT Xiufang Zhang, Nanming Zhao, Yandao Gong, Tsinghua University Prof. Spector, MIT  | |
| 10 | Blood Vessels Heart Valves Discussion: Comparative Analysis of Tissue Engineering Strategies  | Prof. Schoen, Harvard Medical School Dr. W. B. Li, Tsinghua University Prof. Spector, MIT  | |
| 11 | Urinary Tissues/Organs Clinical Applications and Underlying Principles  | Prof. Atala, MIT Prof. Y. Cao, Tsinghua University  | Homework 3 due | 
| 12 | Bone Regeneration Cartilage Repair Discussion: Review  | Dr. Yu Xing, Tsinghua University, and Prof. Yan Wang, M. D., General Hospital of Peoples' Liberation Army Prof. Spector, MIT Prof. Spector, MIT  | Report due | 
| 13 | Federal Regulatory Issues for Tissue Engineering Products in the U.S., China, and Other Countries Brain Repair Review  | Prof. Spector, MIT Prof. Cui, Tsinghua University Prof. Spector, MIT / Prof. Cui, Tsinghua University  | Homework 4 due | 
| 14 | Quiz 2 | ||