Courses:

Course Info

• Course Number / Code:
• 5.069 (Spring 2008) 
• Course Title:
• Crystal Structure Analysis 
• Course Level:
• Graduate 
• Offered by :
• Massachusetts Institute of Technology (MIT)
  Massachusetts, United States  
• Department:
• Chemistry 
• Course Instructor(s):
• Dr. Peter Mueller 
• Course Introduction:
•  
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  5.069 Crystal Structure Analysis
  
  
  
  

  Spring 2008

  
  
  

  
  
  

  Course Highlights

  
  
  

  
  
  5.069 Crystal Structure Analysis
  
  
  
  

  Spring 2008

  
  
  

  

  Molecular model of the amino acid tyrosine with experimental electron density in front of an X-ray diffractometer at MIT. The tyrosine is part of the crystal structure of phosphoglycerate mutase from M. tuberculosis. See Mueller, P., et al. Acta Cryst D61 (2005): 309-315. (Figure and photograph by Dr. Peter Mueller.)

  
  
  

  Course Description

  
  
  

  This course covers the following topics: X-ray diffraction: symmetry, space groups, geometry of diffraction, structure factors, phase problem, direct methods, Patterson methods, electron density maps, structure refinement, how to grow good crystals, powder methods, limits of X-ray diffraction methods, and structure data bases.

  
  

  *Some translations represent previous versions of courses.